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ηγωεϊ εδεγςεϊ μςιϊεπεϊ

θας ξςγλπϊ ςμ ϊεφΰεϊ πιρει χμιπι ωμα II ωμ TALAMPANEL μθιτεμ α-ALS

17/05/2010 θας δεγιςδ διεν ςμ ϊεφΰεϊ πιρει χμιπι ωμα II δξλεπδ ALSTAR. δπιρει ϊελπο μΰξεγ ΰϊ ιςιμεϊ, αθιηεϊ εραιμεϊ δθιτεμ αθμξτπμ (Talampanel) μδτηϊϊ δδϊγψγψεϊ δϊτχεγιϊ αηεμι ALS. ϊεφΰεϊ δπιρει ΰξπν δγβιξε λι δθιτεμ αθμξτπμ αθεη μηεμι ALS , ΰεμν δξηχψ μΰ δωιβ ΰϊ διςγ δχμιπι δψΰωεπι λτι ωδεβγψ ξψΰω.

"ςμ ΰσ ϊχεεϊιπε μτϊη θιτεμ ηγωπι μωιτεψ δδϊξεγγεϊ ςν ξημδ ξβαιμδ ζε, θμξτπμ μΰ δελιη ΰϊ διςιμεϊ δγψεωδ, μξψεϊ ωπξφΰ αθεη μωιξεω." ΰξψ ξωδ ξπεψ, ρξπλ"μ αλιψ μτιϊεη ξεφψιν ιιηεγιιν αθας. "δψηαϊ χε δξεφψιν διιηεγιιν ωμπε, ςμ ιγι ξηχψ ετιϊεη τπιξι ετιϊεη ςρχι, διΰ ημχ ξο δΰρθψθβιδ ΰψελϊ δθεεη ωμ θας. δξξφΰιν δμμε μΰ ιωτιςε ςμ ιλεμϊπε μδωιβ ΰϊ διςγιν μωπϊ 2015. ΰπε πξωικ ατιϊεη ξεφψιν ηγωπιιν δξξεχγιν αϊηεξιν ωμ πειψεμεβιδ, ΰεθεΰιξεπεμεβιδ εΰεπχεμεβιδ."

ΰεγεϊ δξηχψ
ξηχψ δ ALSTAR διπε πιρει ωμα II βμεαμι, ψα ξψλζι, ΰχψΰι, λτεμ ρξιεϊ, ωπςψκ αχαεφεϊ ξηχψ ξχαιμεϊ (λεμμ χαεφϊ αιχεψϊ) εδϊχιιν α-25 ξψλζιν αψηαι ΰψδ"α, χπγδ, ΰιψετδ ειωψΰμ. δξηχψ δχισ 559 ηεμι ALS ΰωψ δεχφε ΰχψΰιϊ μχαμ θιτεμ αθμξτπμ 25mg ΰε θμξτπμ 50mg ωμεω τςξιν αιεν ΰε θιτεμ ατμφαε μΰεψκ τψχ ζξο ωμ 52 ωαεςεϊ. μλμ δηεμιν πιϊπδ δΰτωψεϊ μδωϊξω αϊλωιψ ψιμεζεμ (Riluzole) αξχαιμ μθιτεμ αθμξτπμ (83 ΰηεζ ξο δηεμιν διε ξθετμιν αψιμεζεμ ςν ϊηιμϊ δπιρει). δξγγ δςιχψι μδφμηϊ δπιρει δεβγψ λωιπει αξγγ δ-ALSFRS-R, ρεμν μδςψλϊ δϊγψγψεϊ ϊτχεγιϊ αηεμι ALS.

ΰεγεϊ θψωϊ ΰξιεθψετιϊ φιγιϊ (ALS)
ALS διγεςδ βν λ"ξημϊ με βψιβ," ςμ ων δρτεψθΰι δξτεψρν ωημδ αδ, διπδ ξημδ ξϊχγξϊ εξπεεπϊ ωμ δξςψλϊ δξεθεψιϊ, δξεαιμδ μωιϊεχ εαρετε ωμ γαψ μξεεϊ ςτ"ι ψεα ϊεκ ωμ 3-5 ωπιν ξξεςγ δϊτψφεϊ δξημδ. αξψαιϊ δξχψιν ριαϊ δξεεϊ διπδ λωμ πωιξϊι. ριξτθεξιν ξϊχγξιν λεμμιν ηεμωϊ ωψιψιν αβτιιν, δϊςεεϊεϊ εδϊλεεφεϊ ωψιψιν, μιχειιν αγιαεψ, χωιιν ααμιςδ λξε βν μιχειι πωιξδ. αΰψδ"α εαΰιψετδ ξΰεαηπιν ξγι ωπδ, μξςμδ ξ-10,000 ΰιω ληεμιν α- ALS εδδςψλδ διΰ λι μτηεϊ 50,000 ΰιω αψηαι δςεμν ηεμιν αALS αλμ ζξο πϊεο.

ΰεγεϊ θας
θας ϊςωιεϊ τψξφαθιεϊ ας"ξ διπδ ηαψδ βμεαμιϊ ωαριρδ αιωψΰμ εΰηϊ ξ-15 δηαψεϊ δτψξφαθιεϊ δξεαιμεϊ αςεμν. θας, δξϊξηδ αιιφεψ ϊψετεϊ βπψιεϊ ειιηεγιεϊ ειιφεψ ηεξψιν τςιμιν μϊςωιιδ δτψξφαθιϊ, διπδ δηαψδ δξεαιμδ αςεμν αϊηεν δβπψιχδ. μθας ΰϊψι ιιφεψ, ξηχψ, ωιεεχ εδτφδ αιωψΰμ, αφτεο εαξψλζ ΰξψιχδ εαΰιψετδ. ιεϊψ ξ-80% ξξλιψεϊιδ ωμ δχαεφδ δο μφτεο ΰξψιχδ εΰιψετδ.

Teva's Safe Harbor Statement under the U. S. Private Securities Litigation Reform Act of 1995: The statements, analyses and other information contained herein relating to the proposed acquisition and anticipated synergies, effect on earning and financial and operating performance, including estimates for growth, anticipated positions in certain markets and shares in such markets, the markets for Teva's and ratiopharm's products, the future development and operation of Teva's and ratiopharm's business, as well as other statements including words such as "anticipate," "believe," "plan," "estimate," "expect," "intend," "will," "should," "may" and other similar expressions, are "forward-looking statements" under the Private Securities Litigation Reform Act of 1995. Such statements are made based upon management's current expectations and beliefs concerning future events and their potential effects on the company. Actual results may differ materially from the results reflected in these forward-looking statements. Important factors that could cause or contribute to such differences include whether and when the proposed acquisition will be consummated and the terms of any conditions imposed in connection with such closing and the receipt of any required regulatory or other approval for the consummation of the proposed acquisition, Teva's ability to rapidly and efficiently integrate ratiopharm's operations in a seamless manner and achieve expected synergies, and diversion of management time on merger-related issues, as well as our ability to accurately predict future market conditions and successfully develop and commercialize additional pharmaceutical products, the introduction of competing generic equivalents, the extent to which we may obtain U.S. market exclusivity for certain of our new generic products and regulatory changes that may prevent us from utilizing exclusivity periods, potential liability for sales of generic products prior to a final resolution of outstanding patent litigation, including that relating to the generic versions of Neurontin®, Lotrel®, Protonix® and Eloxatin®, potential tax liabilities which may arise should our arrangements, including our intercompany arrangements, be challenged and determined to be inappropriate, the current economic conditions, competition from brand-name companies that are under increased pressure to counter generic products, or competitors that seek to delay the introduction of generic products, the effects of competition on our innovative products, especially Copaxone® sales, including potential oral and generic competition for Copaxone®, dependence on the effectiveness of our patents and other protections for innovative products, the impact of consolidation of our distributors and customers, the impact of pharmaceutical industry regulation and pending legislation that could affect the pharmaceutical industry, our ability to achieve expected results though our innovative R&D efforts, the difficulty of predicting U.S. Food and Drug Administration, European Medicines Agency and other regulatory authority approvals, the uncertainty surrounding the legislative and regulatory pathway for the registration and approval of biotechnology-based products, the regulatory environment and changes in the health policies and structures of various countries, supply interruptions or delays that could result from the complex manufacturing of our products and our global supply chain, our ability to successfully identify, consummate and integrate acquisitions, the potential exposure to product liability claims to the extent not covered by insurance, our exposure to fluctuations in currency, exchange and interest rates, significant operations worldwide that may be adversely affected by terrorism, political or economical instability or major hostilities, our ability to enter into patent litigation settlements and the intensified scrutiny by the U.S. government, the termination or expiration of governmental programs and tax benefits, impairment of intangible assets and goodwill, environmental risks, and other factors that are discussed in this report and in our other filings with the U.S. Securities and Exchange Commission ("SEC").

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